Rebooted and Rising

. May 29, 2013.

The rebooted Ann Arbor drug development company, Esperion, closed on $33 million funding round last month just before reporting the success of its Phase 2 clinical trials of its cholesterol lowering therapy. Esperion was resurrected by its original founder Roger Newton, who relicensed its name and intellectual property in 2008 from Pfizer.

The company is developing a therapy from the molecule ETC-1002 that targets low-density lipoprotein (LDL), the so-called bad cholesterol that endangers the health of 9 million people. Company officials reported that its therapy lowered LDL cholesterol up to 43 percent in Phase 2 trials.

The funding will allow the company to continue trials and, analysts speculate, take the company public next year.

Newton, who started the original Esperion, led the team that developed Lipitor. He sold the company to Pfizer in 2004 for $1.3 billion. Pfizer eventually shut the company down, allowing Newton to buy back the patent for ETC-1002 for $22.75 million. Esperion is based in the Michigan Life Science and Innovation Center incubator in Plymouth Township.

Trending

Casablanca: Comfortable, Down-To-Earth Moroccan Cuisine

Casablanca, on Washtenaw, close to Downtown Ypsilanti, has a comfortable, down-to-earth atmosphere, hiding it’s 35-year-ago provenance as a Taco Bell. The manager/owner, Mohammad Mohammad, is hands-on, ensuring satisfaction for each customer, assuring that each dish placed on the table is properly presented. The abundant natural light from ample windows gives the dining area a warm,

Cullen Washington, Jr.’s Meditations On Interconnectedness, Vivility, Democracy And Inclusion

In Ancient Greece, the agora was a central public space, meaning “gathering place” or “assembly.” The agora served as a political, commercial and social hub and was also where Socrates found himself in trouble because of his philosophical inquisitions. In The Public Square, an exhibit on view at the University of Michigan Museum of Art

Third Monk Brewery: Empowering Local Performers With Licensing Agreements

Jeff Robinson can hear the music of the brew. After working as an audio engineer for nearly 30 years, the owner of South Lyon’s Third Monk Brewing doesn’t see that career as dissimilar: “…malt is the bass,” he says, “and hops are the treble, and the yeast is the mastering. I can take components of

Courtroom installation explores what is fair and equitable in the legal system

We human beings are a storytelling species. Our social institutions— religious, legal and cultural— are based on narratives that may be fanciful or fact-based or influenced by precedent. But they are also ever-evolving. Throughout the winter and spring of 2020, Courtney McClellan, this year’s Roman J. Witt Artist in Residence at the University of Michigan