Rebooted and Rising

. May 29, 2013.
Esperion-logo

The rebooted Ann Arbor drug development company, Esperion, closed on $33 million funding round last month just before reporting the success of its Phase 2 clinical trials of its cholesterol lowering therapy. Esperion was resurrected by its original founder Roger Newton, who relicensed its name and intellectual property in 2008 from Pfizer.

The company is developing a therapy from the molecule ETC-1002 that targets low-density lipoprotein (LDL), the so-called bad cholesterol that endangers the health of 9 million people. Company officials reported that its therapy lowered LDL cholesterol up to 43 percent in Phase 2 trials.

The funding will allow the company to continue trials and, analysts speculate, take the company public next year.

Newton, who started the original Esperion, led the team that developed Lipitor. He sold the company to Pfizer in 2004 for $1.3 billion. Pfizer eventually shut the company down, allowing Newton to buy back the patent for ETC-1002 for $22.75 million. Esperion is based in the Michigan Life Science and Innovation Center incubator in Plymouth Township.

Trending

Detroit Gallery Crawl

Explore the art scene As the weather in Michigan turns cool, if you are curious about Detroit’s art scene and in the mood for a short 45 minute road trip, now is a great time to head downtown. When I began exploring Detroit several years ago, my hunt for significant art and artists was more

A Place to Co-Operate

The CoOp’s community-focused approach is music to our ears “The vision was, honestly, to bring people together,” says Frances Master, one of six UM students who operate The CoOp, a space inside Openfloor Studio (231 S. State St.). Undeniably, it is refreshing to hear that motivation for creating opportunities to experience live music, as that’s

Constant Buzz

Dominick’s boasts a long history (and an even longer menu) If you ask the townies, “Ann Arbor has changed over the years.” If you ask the busy and bustling crowds of U-M freshmen, they’ll ask: “What?” So, who’s right— the aging hippies who complain about the changing times, or the young newbies eagerly awaiting the

A Wicked Good Time at The Michigan & State

Halloween season is upon us, and the Michigan and State Theaters are offering up treats with hardly a trick in sight. Those who revel in all things Halloween should start marking calendar dates because there’s a lot to scream about all month long— after all, Halloween comes but once a year, at least officially. Don’t-miss